Are Calico Cats Color Blind. The calico color comes from the females having 2 x genes. The spotted or marbled pattern is a dark blue or metal grey color.
While pedigreed black cats have a tendency towards bold orange eyes and white cats tend to have blue eyes, there's very little to connect coat color with eye color. Many cat lovers believe there's no such thing as a calico male cat and that it is genetically impossible. Also in female calico cats the genes which produce color are found on the x chromosome and each hair cell expresses one x allele or the other giving rise to a random pattern of color in their fur.
This has to do with chromosomes that carry certain color genes, and you can read more about that here.
According to irish folklore, calico cats can even cure warts. Many cat lovers believe there's no such thing as a calico male cat and that it is genetically impossible. Why buy a calico kitten for sale if you can adopt and save a life? Unlike what some people think, they're not different breeds.